While there are many neurodegenerative diseases, Huntington's disease is an inherited disorder that causes the brain's nerve cells to slowly die off. The disease is highly debilitating and causes a variety of symptoms that are difficult to manage, including unsteady gait and involuntary body movement, as well as the decline of mental faculties and even severe problems with mood. There are as many as 30,000 people in the United States with Huntington's disease and nearly 100 percent of the cases were inherited.
A person can have the disease when the parents have Huntington's disease (HD) and this is true even if only one of the parents has the mutated Huntingtin gene. A child will have 50 percent chance that the disease will also be acquired. While all people on Earth have the HD gene in them, it is a mutated form of the gene which causes the disease to develop. A parent might not pass the mutation to the child, and that child will be at no risk of developing the disease or passing on to their offspring. However, if the mutation is present, then the child not only will develop the disease at some point, he or she also might very well pass the gene onto their own offspring. A simple blood test is available to determine whether or not a person has the mutation.
Early symptoms observed from people with this disease are mood swings, irritability, and also depression. First symptoms can also be involuntary movements or abnormal movements (known as chorea). When the disease progresses, concentration can be impaired and slurred speech can occur. There is no cure yet of the disease and medications are used only to help treat the symptoms observed.
The focus and concentration are only on the symptoms because there is no known cure yet or not yet discovered or even on how to reverse the disease and even the current treatments are not particularly successful at dealing with symptoms. Early symptoms can occur during childhood, but this is rare and it is far more typical to not have symptoms until after the age of 30 or perhaps older. After the first symptoms begin to appear, life expectancy is generally around 20 years and the rate of progression varies from person to person.
While there is no way discovered to stop the disease yet, there are continuous clinical researches being done to understand how this disease causes so much damage to the human body and ways to combat it. The gene that causes the Huntington disease was discovered in 1993 and since the discovery; clinical research has been done to find cure and treatment for the disease. Scientific tests are done to enable for scientists to see what the defective gene will do to damage the brain and how it also affects the human body's chemistry.
The specific protein found in the HD gene of the person with this disease is known as the Huntingtin protein. This specific protein will grow abnormally long when gene mutation occurs, so medical researchers are studying this protein and the mutation of the protein. Biotechnology firms are around to provide services to help in the clinical research conducted for this specific protein, the HD protein. Studies These biotech companies provide helpful services such as N-terminal sequencing and protein sequencing and protein analysis, all of which further scientific research.
A person can have the disease when the parents have Huntington's disease (HD) and this is true even if only one of the parents has the mutated Huntingtin gene. A child will have 50 percent chance that the disease will also be acquired. While all people on Earth have the HD gene in them, it is a mutated form of the gene which causes the disease to develop. A parent might not pass the mutation to the child, and that child will be at no risk of developing the disease or passing on to their offspring. However, if the mutation is present, then the child not only will develop the disease at some point, he or she also might very well pass the gene onto their own offspring. A simple blood test is available to determine whether or not a person has the mutation.
Early symptoms observed from people with this disease are mood swings, irritability, and also depression. First symptoms can also be involuntary movements or abnormal movements (known as chorea). When the disease progresses, concentration can be impaired and slurred speech can occur. There is no cure yet of the disease and medications are used only to help treat the symptoms observed.
The focus and concentration are only on the symptoms because there is no known cure yet or not yet discovered or even on how to reverse the disease and even the current treatments are not particularly successful at dealing with symptoms. Early symptoms can occur during childhood, but this is rare and it is far more typical to not have symptoms until after the age of 30 or perhaps older. After the first symptoms begin to appear, life expectancy is generally around 20 years and the rate of progression varies from person to person.
While there is no way discovered to stop the disease yet, there are continuous clinical researches being done to understand how this disease causes so much damage to the human body and ways to combat it. The gene that causes the Huntington disease was discovered in 1993 and since the discovery; clinical research has been done to find cure and treatment for the disease. Scientific tests are done to enable for scientists to see what the defective gene will do to damage the brain and how it also affects the human body's chemistry.
The specific protein found in the HD gene of the person with this disease is known as the Huntingtin protein. This specific protein will grow abnormally long when gene mutation occurs, so medical researchers are studying this protein and the mutation of the protein. Biotechnology firms are around to provide services to help in the clinical research conducted for this specific protein, the HD protein. Studies These biotech companies provide helpful services such as N-terminal sequencing and protein sequencing and protein analysis, all of which further scientific research.
About the Author:
Armand Zeiders loves writing about biomedical research. For more information about N-terminal sequencing service, or to find more information about custom recombinant protein services, please check out the PrimmBiotech.com site now.
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